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Merge multiple GWAS datasets

Source: R/data-helpers.R
merge_gwas.Rd

Combine results from multiple GWAS into a single data.frame with a study column identifying the source. Useful for multi-trait comparisons and meta-analysis visualization.

Usage

merge_gwas(..., by = NULL)

Arguments

...

Named gwas_data objects or data.frames. Names become the study column values.

by

Columns to match variants across studies. Default uses SNP if available, otherwise CHR + BP.

Value

A data.frame with an added study column.

Examples

data(example_gwas)
trait1 <- example_gwas
trait2 <- example_gwas
trait2$P <- runif(nrow(trait2))
merged <- merge_gwas(BMI = trait1, Height = trait2)
head(merged)
#> A gwas_data object: 6 variants across 4 chromosomes
#>   Min p-value: 6.81e-03
#>   Lambda GC:   7.391
#>   Columns:     CHR, BP, SNP, P, BETA, SE, A1, A2, AF, study